Found 23 matching trials
A Safety and Efficacy Study of Concomitant Administration of ChAd63/MVA ME-TRAP + RTS,S PHASE1 The purpose of this study is to assess two types of new malaria vaccines in...
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NIHR WTCRF, University Hospital Southampton NHS Foundation Trust
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AdCh63 ME-TRAP and MVA ME-TRAP Malaria Vaccines Evaluation in Healthy Children in a Malaria Endemic Area PHASE1 Infants in malaria-endemic regions of Africa are an important target for va...
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Medical Research Council Laboratories
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A Challenge Study to Assess the Protective Efficacy of Two Malaria Vaccine Candidates PHASE1 This study aims to assess the safety and effectiveness of four new candidat...
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Centre for Clinical Vaccinology and Tropical Medicine
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A Study of AdCh63 ME-TRAP Alone and With MVA ME-TRAP PHASE1 This is an open label phase I study, to assess the safety of a novel malari...
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Lister Ward, Department of Infection and Tropical Medicine, Northwick Park Hospital
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A Study to Determine if New Types of Malaria Vaccines Are Safe, Effective and Lead to Immunity in Kenyan Adults PHASE2 This is a phase IIb clinical trial in malaria-exposed individuals to assess...
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KEMRI/Wellcome Trust Programme, Centre for Geographic Medicine Research - Coast
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A Phase I/IIa Sporozoite Challenge Study to Assess the Efficacy of Candidate Combination Malaria Vaccine Approaches Using the ChAd63 and MVA Vectors Encoding the Antigens ME-TRAP, CS and AMA1 PHASE1 This is an open label, multi-centre phase I/IIa sporozoite-challenge trial ...
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Wellcome Trust CRF, Southampton General Hospital
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Malaria Infection Diagnosed by Polymerase Chain Reaction (PCR) as a Means of Evaluating Pre-erythrocytic Candidate Malaria Vaccines PHASE1 The ability to test candidate pre-erythrocytic stage malaria vaccines, usin...
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Medical Research Council Laboratories
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An Efficacy Study of IV Boosting With ChAd63/MVA ME-TRAP PHASE1 Plasmodium falciparum Malaria remains a major global health problem with ap...
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NIHR Clinical Research Facility, Hammersmith Hospital
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A Study to Assess the Safety and Immunogenicity of a Candidate Malaria Vaccine Using Novel Routes of Administration PHASE1 The purpose of this study is to assess the safety and immunogenicity of nov...
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Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital
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Efficacy of Malaria Vaccines in Kenyan Adults PHASE2 Malaria transmission is falling in some parts of Africa as bed nets and ant...
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KEMRI/Wellcome Trust Programme, Centre for Geographic Medicine Research - Coast
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